Summary from the GEO: "Transcriptional profiling of HUVECs with or without irradiation." Overall design from the GEO: " mRNA profiles of endothelial cells with or without irradiation were generated by deep sequencing using Illumina HiSeq X10. HUVEC cells were collected before and 5 and 72 hrs post-irradiation. Three biological replicates for each condition were sequenced." The data was from a...

Summary from the GEO: "The thymus is extremely sensitive to damage but also has a remarkable ability to repair itself. However, the mechanisms underlying this endogenous regeneration remain poorly understood and this capacity diminishes considerably with age. To identify alternate regeneration pathways in the thymus, we performed an unbiased transcriptome analysis of the non-hematopoietic (CD45-)...

Summary from the GEO: "A single-cell suspension was loaded into the Bio-Rad ddSEQ Single-Cell Isolator on which cells were isolated, lysed and barcoded in droplets. Droplets were then disrupted and cDNA was pooled for second strand synthesis. Libraries were generated with direct tagmentation followed by 3’ enrichment and sample indexing using Illumina Nextera library prep kit. Pooled libraries were...

Summary from Dryad: "Abstract: Lymphangiogenesis is the process by which new lymphatic vessels grow in response to pathologic stimuli such as wound healing, inflammation, and tumor metastasis. It is well-recognized that growth factors and cytokines regulate lymphangiogenesis by promoting or inhibiting lymphatic endothelial cell (LEC) proliferation, migration and differentiation. Our group has shown...